Category Archives: Health

Why we get sick when the weather is cold

Have you, as I have, noticed that many of your friends and acquaintances are sick this winter? Or maybe you yourself got the cold or flu?

We are told that it’s an old wife’s tale that cold weather makes us sick.

Well, it turns out that the old wife’s tale is true!

 

A new study, “Cold exposure impairs extracellular vesicle swarm–mediated nasal antiviral immunity,” coauthored by six scientists, published in The Journal of Allergy and Clinical Immunology, Dec. 6, 2022, found the underlying biological mechanisms for why there is seasonal variation in respiratory viral infections.

Below are excerpts from the article:

Upper respiratory tract infections (URIs) pose a significant public health burden in terms of decreased productivity, absenteeism at work or school, and health care system overload. URIs may be associated with multiple clinical sequelae, such as otitis media, sinusitis, bronchiolitis, pneumonia, and exacerbation of asthma or chronic obstructive pulmonary disease.

Seasonal variation in increased URI prevalence, morbidity, and mortality during the winter period has been well recognized. These adverse outcomes may be further exacerbated by socioeconomic and behavioral factors as well as age, sex, and comorbidities…. Accumulating evidence suggests that temperature and humidity may independently or jointly contribute to the risk of respiratory viral infections due to changes in host susceptibility. Similarly, recent fundamental research exploring the underlying molecular mechanisms demonstrates that cold temperature may impair host innate immune response to viral infections.

The nasal cavity is one of the initial contact points between the external environment and the human body; it is highly sensitive to changes in ambient temperature. The nasal mucosal barrier therefore represents the front line of defense against exposure to inhaled respiratory pathogens through multiple host immune mechanisms. The physical barrier function of the nasal mucosa can prevent pathogens from entering the body through the production of mucus glycoproteins, mucociliary clearance, and epithelial tight junctions. The nasal epithelial cells also play important roles in the initiation, maintenance, and regulation of innate immunity. These defense mechanisms are constitutive and can be activated by both membrane-bound and cytoplasmic pattern recognition receptors that recognize pathogen-associated molecular patterns commonly found in viruses. One of the best characterized classes of pattern recognition receptors is the Toll-like receptor (TLR)family, which are transmembrane receptors expressed on multiple cell types, including nasal epithelial cells. TLRs recognize components of invading microbes and trigger the first line of innate immune and inflammatory responses to combat infectious agents. Within the TLR family, TLR3 is considered a major mediator of cellular defense to viral infection, as it responds to double-stranded RNA (dsRNA), a common by-product of virus replication. While these strategies occur at the level of the epithelial cell, recent evidence has shown that active host mucosal defense to bacteria extends into the mucus itself through the epithelial release of antimicrobial extracellular vesicle (EV) swarms. EVs are lipid-bound vesicles secreted by cells into the extracellular space and have been reported in virtually all human biological fluids, including blood, lymph, and nasal mucus…. Accumulating evidence has shown that in addition to their previously described antibacterial role, EVs may also regulate innate immune responses to viral infections. This occurs through the functional delivery of antiviral agents, such as microRNAs (miRNAs), into neighboring or distant recipient cells…. Previous studies have reported that several miRNAs have direct antiviral effects or regulate the inflammatory pathways, thereby enhancing antiviral immunity against infections. In addition to transport of antiviral agents between cells, EVs can also exert direct virion neutralization by binding to virus ligands via surface receptors and block their entry to host cells.

The scientists ran a number of experiments and found that when the temperature is reduced by as little as 5 degrees Centigrade, “Cold exposure impairs TLR3-dependent EV secretion and miR-17 abundance, which abrogates antiviral activity.” In other words, exposure to cold temperature impairs the body’s secretion of the extracellular vesicles (EV) that regulate our bodies’ innate immune responses to viral infections. 

The study concludes:

[T]he potent antiviral functions mediated by TLR3-dependent EVs are impaired by cold air conditions via a 41.9% decrease in total EV release as well as reduced miRNA packaging (23.8%) and antiviral surface receptor binding activity (24.4% and 77.2%) of individual EV….

Many respiratory viruses initiate infection in the nasal cavity, which is the first region of contact of inhaled respiratory pathogens and is highly sensitive to changes in ambient air temperature. The diminished innate immune responses to viral infections at cool temperatures could thereby create a more permissive environment for virus replication compared to warm temperatures…. [I]nhaling cool air in the winter season might impair the antiviral immune defense functions mediated by TLR3-stimulated EVs and decrease resistance to infections by reducing the host cell temperature within the anterior nasal mucosa. Our observations revealed that exposure to cold resulted in increased host susceptibility to respiratory viruses, providing a potential immunologic mechanism for seasonal variation in URIs.

~E

An act of kindness: Hody Childress donated money to pharmacy for those who could not afford medication

A generous man: Hody Childress (center)

God Bless Hody.

From Daily Mail:

“An Alabama farmer spent some of the little money that he had to help members of his community to pay for their medical bills. Not even Hody Childress’s family members knew about his generosity until shortly before his death at the age of 80 on January 1.

The revelation about his acts was first revealed to many at his January 5 funeral, after the town’s pharmacist told family members.

Childress’s daughter Tania Nix told The Washington Post that she didn’t know what prompted her father to go to Geraldine Drugs in Geraldine, Alabama, a town of around 900, each month and give $100 to the pharmacist to help those struggling.

Nix did speculate that when her mother struggled with multiple sclerosis, her medical bills and drugs were expensive. Her mother, Peggy, passed away in 1999. He began his altruistic tradition in 2012.

Nix said that a woman recently wrote to her to tell her that Childress’s money allowed her to afford an EpiPen for her son, while another said that she burst into tears in the store when she was told that there was a fund that would help her to pay for her and her daughter’s prescription.

The pharmacist at the drug store, Brooke Walker said that Childress told her when he first handed over the money: ‘Don’t tell a soul where the money came from – if they ask, just tell them it’s a blessing from the lord.’

Nix said that a woman recently wrote to her to tell her that Childress’s money allowed her to afford an EpiPen for her son, while another said that she burst into tears in the store when she was told that there was a fund that would help her to pay for her and her daughter’s prescription.

The pharmacist at the drug store, Brooke Walker said that Childress told her when he first handed over the money: ‘Don’t tell a soul where the money came from – if they ask, just tell them it’s a blessing from the lord.’

The pharmacist told a family member that she didn’t let Childress’s donation go on painkillers, only antibiotics and life-sustaining medication.

On two occasions she used the money for non-medical reasons, once to help a woman who was in an abusive relationship to get back on her feet and once to help an elderly man who was caring for his special needs son and his wife, who had broken her hip, to pay for a used washer and dryer.

Nix told WaPo that her father told about his donations as he became gravely ill with chronic obstructive pulmonary disease over the holidays.

She said: ‘He told me he’d been carrying a $100 bill to the pharmacist in Geraldine on the first of each month, and he didn’t want to know who she’d helped with it — he just wanted to bless people with it.’

Read the whole story here.

h/t Breitbart

DCG

Amazing technology: Mind-reading brain implant allows man to “speak”

This is just incredible.

A man who was injured in a car crash 18 years ago was left unable to speak. Thanks to researchers and doctors at the University of California San Francisco, he’s now able to “speak” words because of an implant in his brain. Watch:

The patient, known only as “Pancho,” is of course thrilled with the device. Pancho was able to communicate with the doctors and told them he hates the hospital food!

Read all the details at the Daily Mail here.

DCG

Pray for our youth: Transgender doctor says “age is just a number”

In this case, a very profitable number for this doctor…

Dr. Nadia Dowshen specializes in LBGT issues associated with minors and is the medical director and co-founder of the Gender and Sexuality Development Clinic.

A video has resurfaced of her from 2020 claiming that when it comes to performing sex change surgery on minors, “age is just a number.”

She went on to suggest that a child’s maturity was more important than their exact age. Watch the video at the Daily Mail here.

The good doctor says that at the Children’s Hospital of Philadelphia, they perform ‘top surgery’ on patients as young as 14, which involves removing or implanting breasts.

According to the Daily Mail article, when asked about whether there were age limits in place for sex change surgeries, Dr. Dowshen said: ‘It is important to remember that age is a number. But as an adolescent medicine and developmental specialist, we know that where a child is cognitively and socially is more important than that exact number of their age.’

Here’s the kicker:

“Dr. Dowshen was also asked about the potentially life-altering effects of hormone drugs given to transgender minors, which can cause infertilityShe said that many youngsters with gender dysphoria ‘are not interested in having children at all’.

Read the whole article here.

These “gender affirming” surgeries are very costly.  According to costhelperhealth:

“For patients not covered by health insurance, the typical cost of a sex reassignment surgery can range from about $15,000 for just reconstruction of the genitals to about $25,000 for operations on the genitals and chest to $50,000 or more for procedures that include operations to make facial features more masculine or feminine.”

Nice money to be made there for the clinic Dr Dowshen co-founded.

I’d like to see Dr. Dowshen go into a courtroom and tell the judge that when dealing with a minor, “age is just a number.”

These life-altering drugs and surgeries given to confused minors with gender dysphoria causes irreversible damage.

We need to pray that the current trend of mutilating minors comes to a complete stop.

We need to pray for our youth.

DCG

Friday Funnies!

The brilliant Katie Hopkins is a conservative English columnist and media personality.

By the way, we now have indisputable evidence that senile Joe Biden ordered the FBI raid on Mar-a-Lago, Trump’s home in Florida. daniel_g reports:

Although Biden has repeatedly denied ordering the FBI’s raid on Donald Trump’s Mar-a-Lago estate, court documents reveal otherwise.

U.S. District Judge Aileen Cannon on Monday granted Trump’s request to appoint a Special Master to review the documents seized by the FBI during the August 8th raid.

The ruling “temporarily enjoins” or forbids the Biden Administration from “reviewing and using the seized materials” in the DOJ’s investigation of Trump until the review is completed.

“In pages 2-3 of the ruling, Judge Cannon revealed that the Biden regime actually ORDERED the FBI raid to seize documents in Mar-a-Lago,” Infowars reported.

*Image from Infowars*

This directly contradicts repeated denials by Biden.

When asked last month whether the White House coordinated the FBI’s raid with the DOJ, Biden denied having any involvement.

~E

Baby boy finally goes home after heart transplant surgery

Baby Clay was born with FOUR heart defects in November 2020. After many heart surgeries and a heart transplant, Clay is now home with his parents and siblings!

Such a blessing!

h/t Breitbart

DCG

Woman wakes up after in a coma for two years: “Prayers kept her alive”

From Yahoo:

“A West Virginia woman awoke from a years-long coma after being brutally attacked and identified her brother as the assailant, according to local reports.

Wanda Palmer had been in a long term care facility in New Martinsville, West Virginia, after being beaten in her home in June of 2020, according to the West Virginia Metro News. When Palmer was discovered, Jackson County Sheriff Ross Mellenger said she was so savagely attacked, authorities thought she was dead, the paper reported.

Palmer’s care facility contacted authorities last week to let them know the woman had come out of her coma, the Metro News reported.”

Read the whole story here.

The essence of faith is to believe possibiities exist. Wanda’s family must be so happy she is awake and well!

DCG

Woman receives world-first 3D printed ear implant

Amazing technology!

From The Telegraph:

“A young woman has received a 3D printed ear implant made from her own cells, in a scientific development that could “revolutionise” medicine.

The 20-year-old, who was born with a deformity that left her right ear small and misshapen, had the reconstructive surgery in March in the US – part of the first clinical trial to use 3D printing to construct an implant made of living tissue.

“This is so exciting, sometimes I have to temper myself a little bit,” Dr Arturo Bonilla, who performed the surgery in Texas, told the New York Times. “If everything goes as planned, this will revolutionise the way this is done.”

The implant was produced by 3DBio Therapeutics, a regenerative medicine company based in New York, which announced the successful procedure on Thursday. The results are set to be published in a medical journal when an ongoing trial, which includes 11 volunteers, is complete.

The new ear was made from a tiny clump of cells taken from the woman’s right ear, which experts say will reduce the chance that the implant will be rejected from the body. It will continue to regenerate cartilage, meaning it will eventually feel and look like a natural ear.

It is thought to be the first time that a 3D printed implant made of living tissues has been transplanted. 

The company said that, with more research, the same technology could be used for replacement spinal discs, noses and knee menisci – as well as reconstructive tissue for lumpectomies.

“It’s definitely a big deal,” said Adam Feinberg, a professor of biomedical engineering and materials science and engineering at Carnegie Mellon University, who was not involved in the trial. “It shows this technology is not an ‘if’ anymore, but a ‘when’.”

Read the whole story here.

DCG

Sunday Devotional: Whoever loves me will keep my word

John 14:23-29

Jesus said to his disciples:
“Whoever loves me will keep my word,
and my Father will love him,
and we will come to him and make our dwelling with him.
Whoever does not love me does not keep my words;
yet the word you hear is not mine
but that of the Father who sent me.

“I have told you this while I am with you.
The Advocate, the Holy Spirit,
whom the Father will send in my name,
will teach you everything
and remind you of all that I told you.
Peace I leave with you; my peace I give to you.
Not as the world gives do I give it to you.
Do not let your hearts be troubled or afraid.
You heard me tell you,
‘I am going away and I will come back to you.’
If you loved me,
you would rejoice that I am going to the Father;
for the Father is greater than I.
And now I have told you this before it happens,
so that when it happens you may believe.”

“Whoever loves me will keep my word.”

To keep His word is to abide by His commandments — the ten Mosaic commandments, the “greatest” commandment, as well as the “new” commandment to love one another.

Is it that difficult to keep His word by being good?

Not only is being good good for others and society, it is also good for our own selves — our physical and psychological wellbeing. After all, God would not ask us to do something that is harmful to us.

All of which could explain why studies have shown that:

Keeping His word is good for us!

May the peace of Jesus Christ our Lord be with you,

~E

Schools that switched to remote learning harmed children’s educational achievement in math

Here in Oklahoma schools shut down for just six weeks beginning in March 2020 when the pandemic first hit and we didn’t know what to expect. They returned to normal in-school classes in the fall of 2020. Turns out that was really best for the kids.

From Daily Mail:

Students in school districts that relied more heavily on remote learning during the pandemic fell behind in math at a far greater rate than students in states, like Texas and Florida, that stuck to in-person classes, according to a Harvard study.

Nationally, all students have seen a decrease in academic achievement because of the disruption from the pandemic, an issue that has been exacerbated by poverty and race.

But  Prof. Thomas Kane, an economist and director of Harvard’s Center for Education Policy Research, found that kids that were allowed to come to school faired far better than those who were forced to learn over video feed.

‘We estimate that in high poverty schools students lost about half a year of learning if their schools were remote for half a year or more last year,’ Kane told CNN’s Jake Tapper. ‘That’s a large effect.’

The study looked at test scores for 2.1 million American students in 49 states. Math scores suffered more than reading, according to the report.

‘Interestingly, gaps in math achievement by race and school poverty did not widen in school districts in states such as Texas and Florida and elsewhere that remained largely in-person,’ Kane told the Harvard Gazette. ‘Where schools remained in-person, gaps did not widen. Where schools shifted to remote learning, gaps widened sharply.’

Read the whole story here.

DCG